What are Zellweger Spectrum Disorders?

What are Zellweger Spectrum Disorders?

IntroductionCauses and symptomsEpidemiologyDiagnosisTreatment and managementReferencesFurther reading Zellweger spectrum disorders (ZSDs) are a group of rare genetic diseases marked by a lack of functional peroxisomes caused by mutations in various PEX genes. Zellweger spectrum diseases are a subset of peroxisome biogenesis disorders that span a clinical spectrum of severity from severe to lesser phenotypes. Several metabolite … Read more