viral RNA synthesis, origin, and vaccines

In a recent study published in Current Research in Immunologyresearchers analyzed the characteristics of coronaviruses (CoVs) and novel CoV vaccine candidates. Study: Nature of viruses and pandemics: Coronaviruses. Image Credit: 3DJustincase/Shutterstock Background CoVs are a group of positive-strand, enveloped ribonucleic acid (RNA) viruses belonging to the Nidovirales order. There are four generates within the Orthocoronavirinae … Read more

How the Omicron variant shifted the biology of SARS-CoV-2

The current coronavirus disease 2019 (COVID-19) pandemic has been caused by the rapid outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Several SARS-CoV-2 variants of concern (VOCs) have emerged; however, the Omicron variant possesses a phenotype that is significantly different as compared to previous variants, such as the Beta or Delta variants. In … Read more

SARS-CoV-2 variants of concern and biological sex of patients affect molnupiravir efficacy

SARS-CoV-2 variants of concern and the biological sex of patients affect the efficacy of molnupiravir, the first orally available drug approved for outpatient use against COVID-19, according to a new study led by researchers in the Center for Translational Antiviral Research in the Institute for Biomedical Sciences at Georgia State University. SARS-CoV-2, the virus that … Read more

Genetic information from bats may help prevent and manage future pandemics, suggests study

Why are bats often linked to incubating coronaviruses such as those behind COVID-19, SARS and other highly contagious respiratory diseases? A new Tulane University study suggests that the link between bats and coronaviruses is likely due to a long-shared history, and that their genetic information can help us prevent and manage future pandemics. Hannah Frank, … Read more